Why am I getting so hammered on so little wine?

I haven't been able to drink much, due to surgery 7 weeks ago. Now, I have cut waaaay back on my pain meds and don't take any on a day that I plan on indulging in a glass of wine or two. I'm up and walking about pretty good now, even though I have to rest several times a day.
I've discovered that I start feeling a little fuzzy after about 1/4 of a glass and really feel it at the 1/2 glass mark. Certainly by the 3/4 glass mark I ask my husband to pour out the balance of whatever is in my glass. I've learned to pour much smaller glasses.
If I was 21, I'd relish the cheap buzz, but at my (ahem) more mature age, I find it disconcerting.
Do you think this is due to the residual pain meds in my system, the fact that I haven't been drinking since the surgery, or that I'm just not as mobile as I was before the surgery, therefore not burning it off as quickly?
p.s. I'm at the 1/2 glass point now and you have no idea how many times I've had to retype this. Crazy
Original Post
quote:
Now, I have cut waaaay back on my pain meds and don't take any on a day that I plan on indulging in a glass of wine or two. I'm up and walking about pretty good now, even though I have to rest several times a day.

Way back but not entirely? So you're still on some pain meds? And you're still weak enough that you have to rest several times a day?

No idea what was wrong but it sounds like you aren't really 100%. Just like Board-o said, it's worth a discussion with your doctors. In fact, you might want to talk to your doctor about whether you should be having any wine at all. But it seems like there's a pretty good clue to the answer in your question itself.

Here's hoping for a speedy recovery though!
It's hard to tell, not knowing what kind of surgery you had, what medications you are on (pain meds and others), what your age is, other health issues, if any, etc., etc.

I will say this. Your body may have been/probably was "adjusted" to your pre-surgery drinking patterns--the key enzymes in your liver were revved up to match your intake. After your surgery, assuming your alcohol intake stopped, those enzymes returned to a low level, while others in your liver were probably revved up to accommodate the pain medications, and any other medications you may be taking. The interactions of drugs, including EtOH, can be quite complex. Furthermore, if you have been inactive for a while, the muscle loss and change in your metabolism will also have an effect.

Bottom line, as above, you should consult with your physician. I would recommend to NOT mix pain killers and alcohol, and the sooner you can get back to "normal" activity levels, with exercise and proper diet, the better.
I had a spinal fusion on my lower back 7 weeks ago. I'm 54, in good health, only other med is Synthroid for a low thyroid. This is the first time in my life I've been in a hospital for myself.
The Dr. put me on Norco 1-2 tablets every 4 hours or as needed. I am down to 1/2 a tablet 3 times a day, but don't take any if I am going to have a glass of wine that evening. If I'm feeling good, sometimes I'll just take a half pill all day, or not at all
At my 1 month check up, I asked the Dr. about wine and he told me that a glass or two was fine.
I am up to walking 2 times a day for 20 mintues each time, without the walker. The walking is done inside my house so that I don't have to deal with the hills that I live in or any stairs. It's getting pretty boring walking the same loop from bedroom, down hallway, through dining room, living room, kitchen and back to the bedroom. Thus the need for a glass now and again.
I go back to see the Dr. in a week, so will follow up with him then.
I think the question I asked last night was a bit of PWI Roll Eyes but appreciate any input.
quote:
Originally posted by DoubleD:
FWIW, I always get hammered after a small glass of g-man's port!


quote:
Originally posted by g-man
i know that codeine and booze always goes well together.


Well, this might explain it. Cool

And yes, get well soon justme. Keep us posted on what you find out.

PH
quote:
Originally posted by justme:I am down to 1/2 a tablet 3 times a day, but don't take any if I am going to have a glass of wine that evening.


Skipping a couple doses doesn't mean the drug is out of your system. The regime is to keep the level of a drug in your system within a certain range. So, just because it's below that range and isn't so effective with the pain doesn't mean it won't be effective at magnifying your reaction to alcohol or worse.
quote:
Originally posted by yhn:
quote:
Originally posted by justme:I am down to 1/2 a tablet 3 times a day, but don't take any if I am going to have a glass of wine that evening.


Skipping a couple doses doesn't mean the drug is out of your system. The regime is to keep the level of a drug in your system within a certain range. So, just because it's below that range and isn't so effective with the pain doesn't mean it won't be effective at magnifying your reaction to alcohol or worse.


Norco is not a time-release analgesic. The amount if time justme has been leaving between the meds and drinking eliminates a compounding/potentiating effect for most metabolisms.

PH
quote:
Originally posted by PurpleHaze:
quote:
Originally posted by yhn:
quote:
Originally posted by justme:I am down to 1/2 a tablet 3 times a day, but don't take any if I am going to have a glass of wine that evening.


Skipping a couple doses doesn't mean the drug is out of your system. The regime is to keep the level of a drug in your system within a certain range. So, just because it's below that range and isn't so effective with the pain doesn't mean it won't be effective at magnifying your reaction to alcohol or worse.


Norco is not a time-release analgesic. The amount if time justme has been leaving between the meds and drinking eliminates a compounding/potentiating effect for most metabolisms.

PH


I'm not talking about time release. Are you qualified to comment with certainty how long this drug stays in the system? I'm not. Your post comes across as giving him the okay to continue ignoring obvious warning signs instead of consulting a doctor.
quote:
Originally posted by yhn:
Your post comes across as giving him the okay to continue ignoring obvious warning signs instead of consulting a doctor.


If you'd bothered to read my earlier post to her you'd find out this is not the case at all. I reinforced Board-O's initial recommendation that she consult with her physician.

If you'd read her subsequent post, you might have seen that her physician also okayed wine consumption.

Hydrocodone clears the system very quicky and has a half life of just under 4 hours in people with a normal metabolism.

PH
PH, You may have something there. Prior to surgery, I usually had 2 glasses of wine to cut the pain. So going without a drop for over 6 weeks may have reset my Buzz-O-Meter.

SD-Wineaux, I practiced Yoga for many years prior to surgery. The Dr. told me that the best thing to do for my back was to walk, walk, walk, but I'm looking forward to getting back to Yoga eventually.

YHN, don't worry about the gender error. You have no idea how many times I've been told I have big balls. Big Grin

And to everyone else, thank you for your well wishes. I feel so much better now than I did before the surgery and am looking forward to hiking these beautiful mountains next season!
quote:
Originally posted by justme:

And to everyone else, thank you for your well wishes. I feel so much better now than I did before the surgery and am looking forward to hiking these beautiful mountains next season!


I just visited your mountains this past summer. The chance to hike them again would certainly motivate me! Good luck.
quote:
Originally posted by PurpleHaze:
quote:
Originally posted by yhn:
Your post comes across as giving him the okay to continue ignoring obvious warning signs instead of consulting a doctor.


If you'd bothered to read my earlier post to her you'd find out this is not the case at all. I reinforced Board-O's initial recommendation that she consult with her physician.

If you'd read her subsequent post, you might have seen that her physician also okayed wine consumption.

Hydrocodone clears the system very quicky and has a half life of just under 4 hours in people with a normal metabolism.

PH


The doc okayed it and *then* she got a potentially serious warning sign.

Let's see... With a 4 hour half-life and a dose prescribed for about once every 8 hours, and with the effectiveness window I stated, that means 8 hours after the last dose is still above the minimal effective level. So, 16 hours after the last dose is above 1/4 the minimal effective level. So it's not exactly insignificant, is it? And it's clearly not a reaction the doctor anticipated, is it? Whatever the factors causing her reaction, she shouldn't be ignoring these warning signs and drinking away before seeing her doctor again.

Btw, there's a "justme" elsewhere who is a guy. Sorry I didn't re-read the older posts after seeing that irresponsible one.
quote:
Originally posted by yhn:
Sorry I didn't re-read the older posts after seeing that irresponsible one.


Context is important, yhn... so perhaps you should read an entire thread before making claims of irresponsibility. That said, apparently you're still having reading comprehension problems in addition to an inability to do simple mathmatics.

The only comment I made specific to justme's situation was that she consult her doctor. Period. The rest of my posts in relation to this subject had to do with the likelihood of drug interactions in people with normal metabolisms. I was not making, and would never make medical recommendations for anyone.

As far as your math skills are concerned, let me break it down for you. The half-life of a drug has nothing to do with the dosage interval. It has to do with the breakdown of the drug in the system after last ingestion. Each half-life interval reduces the percentage of the original dose by half. Let's assume for the sake of argument, that justme's last dose was at 9PM in the evening prior to her planning on drinking. Again, for the sake of argument let's assume that she waits until the traditional drinking lamp is lit, say 5PM the following day. The percentage of the original dose in her system at that point would be approximately 3.25% of the original dosage. Given the standard 5/325 content of the basic Norco caplet and that justme was down to a 1/2 pill dosage at the time, that would leave 80 micrograms of hydrocodone in her system at the time of her having her first sip of wine.

80 micrograms of hydrocodone and an ounce or two of wine is HIGHLY unlikely to produce the type of cognitive impairment that she described without other significant factors being involved. That is all.

PH
quote:
Originally posted by PurpleHaze:

80 micrograms of hydrocodone and an ounce or two of wine is HIGHLY unlikely to produce the type of cognitive impairment that she described without other significant factors being involved. That is all.

PH


i will say that 50 milligrams and half a bottle of port will certainly destroy most types of cognitive abilities.
quote:
Originally posted by g-man:
quote:
Originally posted by PurpleHaze:

80 micrograms of hydrocodone and an ounce or two of wine is HIGHLY unlikely to produce the type of cognitive impairment that she described without other significant factors being involved. That is all.

PH


i will say that 50 milligrams and half a bottle of port will certainly destroy most types of cognitive abilities.


Uh....that would likely kill you. Or certainly make you very, very ill..... Ack

PH
quote:
Originally posted by PurpleHaze:
The only comment I made specific to justme's situation was that she consult her doctor. Period. The rest of my posts in relation to this subject had to do with the likelihood of drug interactions in people with normal metabolisms. I was not making, and would never make medical recommendations for anyone.

quote:
The amount if time justme has been leaving between the meds and drinking eliminates a compounding/potentiating effect for most metabolisms.


The only reason I wasted my time posting is because she could infer that it was okay to keep drinking before seeing her doctor.

You're still arguing with your silly "I am right, dammit!" math exercise that it's okay for her to drink because you base your math on her having a normal metabolism. You're missing the forest for the trees. If you open a door a little crack for someone looking for an excuse it can be just too tempting to resist. That, is irresponsible.
quote:
Originally posted by yhn:
You're still arguing with your silly "I am right, dammit!" math exercise that it's okay for her to drink....


Please cite a post of mine where I specifically argued that it was OK for justme to drink. You won't be able to, because I DIDN'T!!! Now go cure some olives or something.... Roll Eyes

PH
quote:
i will say that 50 milligrams and half a bottle of port will certainly destroy most types of cognitive abilities.
LOL
Finally some hard data. We know we can trust it because we know it's from first-hand experience! No BS rumors or hearsay or something found on the internet.

justme - make sure to avoid 50mg and 1/2 a bottle of Port.
quote:
Originally posted by PurpleHaze:

Please cite a post of mine where I specifically argued that it was OK for justme to drink.
PH



Well, now you're making me very nervous! I cannot cite a single post of yours where you specifically argued that it is OK for me to drink. I'm not sure exactly what the rules are, but until I read that you approve, I am going to seriously consider whether or not to discontinue my love affair with wine.

God, another life-changing moment on the internet for me! How many more can there possibly be??
quote:
Originally posted by Seaquam:
quote:
Originally posted by PurpleHaze:

Please cite a post of mine where I specifically argued that it was OK for justme to drink.
PH



Well, now you're making me very nervous! I cannot cite a single post of yours where you specifically argued that it is OK for me to drink. I'm not sure exactly what the rules are, but until I read that you approve, I am going to seriously consider whether or not to discontinue my love affair with wine.

God, another life-changing moment on the internet for me! How many more can there possibly be??


Drink to your heart's content, Seaquam.

I am PurpleHaze, and I approve of this message.

Banana

PH
quote:
Originally posted by PurpleHaze:
quote:
Originally posted by Seaquam:
quote:
Originally posted by PurpleHaze:

Please cite a post of mine where I specifically argued that it was OK for justme to drink.
PH



Well, now you're making me very nervous! I cannot cite a single post of yours where you specifically argued that it is OK for me to drink. I'm not sure exactly what the rules are, but until I read that you approve, I am going to seriously consider whether or not to discontinue my love affair with wine.

God, another life-changing moment on the internet for me! How many more can there possibly be??


Drink to your heart's content, Seaquam.

I am PurpleHaze, and I approve of this message.

Banana

PH




Ah, bless you, my friend. I can sleep again. Smile
Everyone can relax. I'm not having a drop until after I see my Dr. which is Monday, thankfully.

I'm sure part of my problem is that since the surgery, I eat a very light lunch. Usually some grapes, cheese & crackers. So when I have a glass with dinner, I'm basically drinking on an empty stomach.

I'm just suprised at how hard the wine hits me because I often eat a very light lunch and haven't had the same reaction.

I'll ask my Dr. what he thinks and will report back.
quote:
Originally posted by g-man:
i know that codeine and booze always goes well together.


Narcotics most certainly potentiate the effects of alcohol. Consider that with alcohol you typically have a "loading dose" effect, or a saturation point that is more dependent on your weight than anything. If your weight didn't change than i would put the blame on the pain meds. I've heard of the same thing from many people....it's normal. Just be careful.
I'm back from my Dr. appointment. He told me that several factors may have contributed to my low tolerance- I've lost about 13 lbs since surgery, have not been eating as I usually do and am not nearly as active.

He was suprised at how easily I'm affected by such a small amount. I was told that if I don't take any meds on the day that I plan to drink, it is ok to have a glass or less of wine, which is all I realy care for at this point. As I begin to return to a more regular diet and activity level, things should stabilize.

He said that there were no concern of having an overdose, more of a concern that I would be unstable walking and may injure my back by stepping wrong or making a movement that I'm not ready for yet.

The great news is that I'm healing quickly and the daily walking I've been doing has helped tremendously! I get to start weaning off the back brace, get to start Physical Therapy and am cleared for travel.

Now to figure out if we want to go to Carmel or Laguna Beach...

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