If you're looking for one night of fantabulous dinner, service n' whatnot. Then you cannot go wrong with Masas, Danko or FdL. For a more casual dining experience that will cost you a lot less than those three, SF will definatly rock your socks off. Even if it's just walking through Chinatown and picking up 3 Pork Buns for $1. (god I love chinatown)

I can recommend I recommend Zuni earlier, and it really is a fantastic restaurant. It's chic n' trendy, but the food is freakin good and won't hurt ya in the wallet. Even if the Chef / Owner is an Alice Waters acolyte.

If you do try Zuni (and I
really recommend that you do) get the Chicken. It's for 2, and it's awesome.
I had lunch last week at Piperade. It opened last year to much fanfare. It's not perfect, but it's a fun place to eat and the food is pretty damn slammin. The desserts are fantabulous. I do recommend just ordering off the tapas menu for great QPR.
And I see that JimmyV just bumped up a pretty old thread full of good stuff. So you can check that out.

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AIM: Drunken Mariachi