By "fake" do you mean counterfeit where the wine has a label that says one thing but it's really something else? Or do you mean that it's not even really wine made from fermented grapes?
As far as counterfeit wine, I wouldn't worry about it. If you're going to open a wine shop, you will source from licensed distributors. As long as the wine hasn't come from China, you're probably OK. You won't be buying from individuals who tell you that they found a secret stash somewhere, or from individuals who want to unload a few bottles.
As far as "spotting" them, that's a crapshoot. The movie mentioned has a few people who've used that story to make their reputations. One in particular said that you can never know a fake wine by tasting it, you have to look at the packaging and do chemical analysis of the glue, glass, paper, ink and even the wine, and she knows more about that than you do so you have to call her.
Again, I wouldn't worry about it. You're not going to be selling small lots of rare wine, at least right off the bat.